SAN VICENTE is the seat of the municipal government of Orion. The barangay derived its name from San Vicente Ferrer, one of the prominent patron saints belonging to the Dominican Order.
The barangay, acknowledged as the center of the old Poblacion, was founded sometime in 1667, the year when Orion was established as a regular town. The present San Vicente was not the center of Orion during the early times. In 1667, the first chapel of Saint Michael Archangel was erected in the old Tutuban area, near the Sto, Domingo River. It was only after the death of Fr.Domingo Ferez, the first parish priest of Orion, that a new church made of bricks was constructed at its present site.